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Preimplantation Genetic Testing at Dr. Pallavi Agrawal’s Clinic

Preimplantation Genetic Testing (PGT) is an advanced genetic testing procedure used during in vitro fertilization (IVF) to screen embryos for genetic disorders before implantation. PGT can help identify embryos that are affected by certain genetic conditions, chromosomal abnormalities, or sex-linked disorders, allowing for the selection of genetically healthy embryos for transfer.

Types of PGT

  1. PGT-A (Aneuploidy Screening): PGT-A is used to screen embryos for chromosomal abnormalities, such as aneuploidy (an abnormal number of chromosomes). This can help reduce the risk of miscarriage and increase the chances of a successful pregnancy.
  2. PGT-M (Monogenic/Single Gene Disorders): PGT-M is used to screen embryos for specific genetic disorders caused by a single gene mutation, such as cystic fibrosis or sickle cell anemia. This can help prevent the transmission of genetic diseases to future generations.
  3. PGT-SR (Structural Rearrangement): PGT-SR is used to screen embryos for structural rearrangements of chromosomes, such as translocations or inversions, which can lead to miscarriage or genetic disorders in offspring.

How Does PGT Work?

  1. IVF Procedure: Eggs are retrieved from the woman’s ovaries and fertilized with sperm in a laboratory to create embryos.
  2. Embryo Biopsy: On the third to fifth day of development, a few cells are removed from each embryo for genetic testing.
  3. Genetic Analysis: The biopsied cells are analyzed for genetic abnormalities using advanced genetic testing techniques.
  4. Embryo Selection: Based on the genetic test results, only genetically healthy embryos are selected for transfer into the woman’s uterus.

Benefits of PGT

  1. Reduced Risk of Genetic Disorders: PGT can help identify and avoid the transfer of embryos affected by genetic disorders, reducing the risk of passing on these disorders to future generations.
  2. Increased Pregnancy Success: By selecting genetically healthy embryos, PGT can increase the chances of a successful pregnancy and live birth.
  3. Emotional Relief: PGT can provide emotional relief to couples at risk of passing on genetic disorders, knowing that they are making informed decisions about their family planning.

Is PGT Right for You?

PGT may be recommended if:

  • You or your partner are carriers of a known genetic disorder.
  • You have a history of recurrent miscarriages or failed IVF cycles.
  • You are of advanced maternal age.

Schedule a Consultation

If you’re considering PGT as part of your fertility treatment, schedule a consultation with Dr. Pallavi Agrawal. She will evaluate your medical history, conduct necessary tests, and recommend the most appropriate treatment plan tailored to your needs.